Romelu Lukaku gave Inter a fifth-minute lead from the penalty spot – Diego Carlos might have been sent off for bringing him down – but Sevilla’s semi-final hero Luuk de Jong overturned the deficit with a pair of fine first-half headers.
Diego Godin’s 35th-minute leveller had Inter swiftly back on terms and the Serie A side appeared to be in the ascendency during a more circumspect second half, until a stunning twist in the tale.
Diego Carlos had been tormented by Lukaku for most of the game but his overhead-kick when Ever Banega’s 74th-minute free-kick was partially cleared took a decisive touch off Inter’s top scorer and flew into the net.
But Lukaku’s own-goal means former Inter’s Chelsea coach Antonio Conte is still waiting for his first major European trophy, as Sevilla took this competition for an incredible sixth time since 2006.
It was cruel for Inter, who were convinced Carlos should have been sent off when he fouled Lukaku for the spot-kick.
At the end of this exhausting season, it would have been understandable for both sides to ease their way into the match. Not a bit of it.
In the second minute, Sevilla wanted a red card when Danilo D’Ambrosio swung an arm at Lucas Ocampos, and they became even angrier when Inter took the lead with their first attack.
Lukaku powered onto Nicolo Barella’s pass and surged past Diego Carlos, who dragged him down with a challenge right out of the Six Nations.
Inter were enraged that the defender – who has now conceded spot-kicks in three consecutive matches – saw only a yellow card, yet seconds later they were ahead when Lukaku beat Bono from the spot to match Ronaldo’s record.
Just as they had against Manchester United, Sevilla did not panic, got their possession game going and scored the equaliser.
Finding space on the right, Jesus Navas delivered a waist-high cross and De Jong drifted between Godin and Stefan de Vrij before connecting with a diving header that Samir Handanovic could only palm into the net.
Referee Danny Makkelie was the busiest man on the pitch as every decision was contested. Players surrounded him at ever flashpoint and after Inter were denied a second penalty when the ball struck Carlos’ hand, Inter coach Antonio Conte was booked for his protests.
Both sides looked dangerous in attack, vulnerable at the back. D’Ambrosio miscued a volley at the far post after stretching for Ashley Young’s cross. Moments later the Inter wing-back lost Ocampos but the Argentine shot wide.
It was another Argentine, Sevilla’s midfield genius Ever Banega, who created their second. His precise free-kick picked out the soaring De Jong at the far post, and the Dutchman guided a magnificent header into the top corner.
Sevilla celebrated raucously yet just like Inter, they could not keep their lead. Once again, Carlos’ foul on Lukaku was costly. This time it was outside the box but the result was the same as Marcelo Brozovic picked out Godin, who nodded past Bono – six years after scoring in the Champions League Final for Atletico Madrid.
At the end of a breathless half, Sevilla came close from another Banega free-kick but this time Ocampos’ header was tipped over.
Having put his team in trouble twice, Carlos got them out of jail at the start of the second half with an excellent sliding block to deny Roberto Gagliardini’s effort from the edge of the box.