Liverpool suffers a shocking sixth consecutive home defeat with Fulham emerging from Anfield with a memorable result to keep their survival hopes alive.
Jurgen Klopp will be hoping to end that run against RB Leipzig in the Champions League on Wednesday.
Mario Lemina struck on the stroke of half-time, capitalising on slack defending from Mohamed Salah to rifle into the far corner from the edge of the penalty area.
The Gabon midfielder became the first Fulham player to score against Liverpool at Anfield since Collins John in March 2006 as they won their first match on the ground since 2012, which on that day came in favour of a Martin Skrtel own goal.
It meant Fulham’s revival, having lost just once in the last seven, are only in the bottom three by having a goal difference three worse than Brighton.
Substitute Sadio Mane was denied an equaliser as the champions pushed to salvage at least a point, but Fulham was able to stand firm brilliantly and move level on points with 17th-placed Brighton.
Just before half-time, Salah took too long to clear the ball on the edge of his box and Lemina nicked it off him before picking out the far bottom corner.
Jurgen Klopp’s made seven changes – including three of his back four – with that in mind were the most between Premier League matches since the 2015-16 season, with the inexperienced pairing of Nat Phillips and Rhys Williams the 16th different centre-back combination to have started in 28 league matches.
It was perhaps unsurprising their first-half performance was disjointed, although they managed twice the number of shots on target (two) in the opening half-hour that they achieved in the entirety of Thursday’s defeat to Chelsea.
Even with Salah, Diogo Jota – making his first start since December after a knee injury – and Xherdan Shaqiri completing a new-look forward line they still did not look like scoring.
The hosts dominated the second half, with Jota forcing a great save out of Areola before Mane hit the crossbar with a header and Neco Williams fired over, but they couldn’t find an equaliser.
Fulham arrow level on points with Brighton and Hove Albion, but they stay in the 18th due to their inferior goal difference.
Next up for them is a tough test against the league leaders, Manchester City, at home.